Solute carrier family 25 member 34 (SLC25A34)

About Solute carrier family 25 member 34

Solute carrier family 25 member 34 (SLC25A34) is a protein from Homo sapiens identified by UniProt accession Q6PIV7, 304 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Solute carrier family 25 member 34
UniProt accession	Q6PIV7
Gene	SLC25A34
Organism	Homo sapiens
Length	304 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.06
pulse pressure measurement · score 0.06
metabolite measurement · score 0.04
Barrett's esophagus · score 0.03
ulcerative colitis · score 0.03
colorectal cancer · score 0.03
Crohn's disease · score 0.02
type 2 diabetes mellitus · score 0.02
colorectal adenocarcinoma · score 0.02
non-alcoholic fatty liver disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PIV7-F1	alphafold	PREDICTED	84.73	—

Amino-acid sequence (304 residues)

METVPPAVDL VLGASACCLA CVFTNPLEVV KTRLQLQGEL QARGTYPRPY HGFIASVAAV ARADGLWGLQ KGLAAGLLYQ GLMNGVRFYC YSLACQAGLT QQPGGTVVAG AVAGALGAFV GSPAYLIKTQ LQAQTVAAVA VGHQHNHQTV LGALETIWRQ QGLLGLWQGV GGAVPRVMVG SAAQLATFAS AKAWVQKQQW LPEDSWLVAL AGGMISSIAV VVVMTPFDVV STRLYNQPVD TAGRGQLYGG LTDCMVKIWR QEGPLALYKG LGPAYLRLGP HTILSMLFWD ELRKLAGRAQ HKGT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards