About BRICHOS domain-containing protein 5
BRICHOS domain-containing protein 5 (BRICD5) is a protein
from Homo sapiens identified by UniProt accession
Q6PL45, 260 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | BRICHOS domain-containing protein 5 |
|---|
| UniProt accession | Q6PL45 |
|---|
| Gene | BRICD5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 260 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- body height · score 0.11
- lean body mass · score 0.09
- body weight · score 0.08
- appendicular lean mass · score 0.08
- fat body mass · score 0.07
- hip circumference · score 0.07
- base metabolic rate measurement · score 0.06
- whole body water mass · score 0.06
- BMI-adjusted hip circumference · score 0.03
- Red cell distribution width · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PL45-F1 | alphafold | PREDICTED | 70.26 | — |
Amino-acid sequence (260 residues)
MEPASCCAER PKPGPTGVKT KPSCGGWRAV SLLLLLLLLV LAAVGVVAGG LLGSAQGPPK PRLQTLRMTL PSPHMPRPNQ TILVDVARNA ATITVTPPQS NHSWAVLFDG QSGCICYRPE EHQVCFLRLM EDSDRETLRL LVDTSKVQEA WVPSQDTHHT QELLAVQGSL EVDPAQAGAL VQRLCMRTPI YWARRAEGES GPLWGKARPS GWFEELGAEP LEIHGTLATG PRRQRLIYLC IDICFPSNIC VSVCFYYLPD
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