About Solute carrier family 2, facilitated glucose transporter member 7
Solute carrier family 2, facilitated glucose transporter member 7 (SLC2A7) is a protein
from Homo sapiens identified by UniProt accession
Q6PXP3, 512 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Solute carrier family 2, facilitated glucose transporter member 7 |
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| UniProt accession | Q6PXP3 |
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| Gene | SLC2A7 |
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| Organism | Homo sapiens |
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| Length | 512 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (21)
Diseases linked to this target (Open Targets).
- aspartate aminotransferase measurement · score 0.04
- blood protein measurement · score 0.04
- leukocyte count · score 0.04
- carbonic anhydrase 6 measurement · score 0.04
- protein measurement · score 0.03
- lung adenocarcinoma · score 0.03
- monocyte percentage of leukocytes · score 0.03
- monocyte count · score 0.03
- granulocyte percentage of myeloid white cells · score 0.02
- lymphocyte:monocyte ratio · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PXP3-F1 | alphafold | PREDICTED | 87.85 | — |
Amino-acid sequence (512 residues)
MENKEAGTPP PIPSREGRLQ PTLLLATLSA AFGSAFQYGY NLSVVNTPHK VFKSFYNETY FERHATFMDG KLMLLLWSCT VSMFPLGGLL GSLLVGLLVD SCGRKGTLLI NNIFAIIPAI LMGVSKVAKA FELIVFSRVV LGVCAGISYS ALPMYLGELA PKNLRGMVGT MTEVFVIVGV FLAQIFSLQA ILGNPAGWPV LLALTGVPAL LQLLTLPFFP ESPRYSLIQK GDEATARQAL RRLRGHTDME AELEDMRAEA RAERAEGHLS VLHLCALRSL RWQLLSIIVL MAGQQLSGIN AINYYADTIY TSAGVEAAHS QYVTVGSGVV NIVMTITSAV LVERLGRRHL LLAGYGICGS ACLVLTVVLL FQNRVPELSY LGIICVFAYI AGHSIGPSPV PSVVRTEIFL QSSRRAAFMV DGAVHWLTNF IIGFLFPSIQ EAIGAYSFII FAGICLLTAI YIYVVIPETK GKTFVEINRI FAKRNRVKLP EEKEETIDAG PPTASPAKET SF
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