About POTE ankyrin domain family member H
POTE ankyrin domain family member H (POTEH) is a protein
from Homo sapiens identified by UniProt accession
Q6S545, 545 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | POTE ankyrin domain family member H |
|---|
| UniProt accession | Q6S545 |
|---|
| Gene | POTEH |
|---|
| Organism | Homo sapiens |
|---|
| Length | 545 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- cancer · score 0.01
- neoplasm · score 0.01
- hepatocellular carcinoma · score 0.00
- myelodysplastic syndrome · score 0.00
- acute myeloid leukemia · score 0.00
- pachyonychia congenita · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6S545-F1 | alphafold | PREDICTED | 63.01 | — |
Amino-acid sequence (545 residues)
MVAEAGSMPA ASSVKKPFGL RSKMGKWCRH CFAWCRGSGK SNVGTSGDHD DSAMKTLRSK MGKWCCHCFP WCRGSGKSNV GTSGDHDDSA MKTLRSKMGK WCCHCFPCCR GSGKSNVGTS GDHDDSAMKT LRSKMGKWCC HCFPCCRGSG KNKVGPWGDY DDSAFMEPRY HVRREDLDKL HRAAWWGKVP RKDLIVMLKD TDMNKKDKQK RTALHLASAN GNSEVVKLLL DRRCQLNILD NKKRTALTKA VQCQEDECAL MLLEHGTDPN IPDEYGNTAL HYAIYNEDKL MAKALLLYGA DIESKNKHGL TPLLLGVHEQ KQQVVKFLIK KKANLNALDR YGRTALILAV CCGSASIVSL LLEQNIDVSS QDLSGQTARE YAVSSRHNVI CQLLSDYKEK QILKVSSENS NPEQDLKLTS EEESQRLKGS ENSQPEEMSQ EPEINKGGDR KVEEEMKKHG STHMGFPENL TNGATADNGD DGLIPPRKSR TPESQQFPDT ENEQYHSDEQ NDTQKQLSEE QNTGILQDEI LIHEEKQIEV AENEF
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