Ras-like protein family member 11A (RASL11A)

About Ras-like protein family member 11A

Ras-like protein family member 11A (RASL11A) is a protein from Homo sapiens identified by UniProt accession Q6T310, 242 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Ras-like protein family member 11A
UniProt accession	Q6T310
Gene	RASL11A
Organism	Homo sapiens
Length	242 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.41
monocyte count · score 0.29
pulse pressure measurement · score 0.26
attention deficit hyperactivity disorder · score 0.23
substance abuse · score 0.23
antisocial behaviour measurement · score 0.23
mitochondrial DNA measurement · score 0.20
mean arterial pressure · score 0.18
serum alanine aminotransferase measurement · score 0.10
creatinine measurement · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6T310-F1	alphafold	PREDICTED	78.59	—

Amino-acid sequence (242 residues)

MRPLSMSGHF LLAPIPESSS DYLLPKDIKL AVLGAGRVGK SAMIVRFLTK RFIGDYEPNT GKLYSRLVYV EGDQLSLQIQ DTPGGVQIQD SLPQVVDSLS KCVQWAEGFL LVYSITDYDS YLSIRPLYQH IRKVHPDSKA PVIIVGNKGD LLHARQVQTQ DGIQLANELG SLFLEISTSE NYEDVCDVFQ HLCKEVSKMH GLSGERRRAS IIPRPRSPNM QDLKRRFKQA LSPKVKAPSA LG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards