About Opsin-5
Opsin-5 (OPN5) is a protein
from Homo sapiens identified by UniProt accession
Q6U736, 354 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Opsin-5 |
|---|
| UniProt accession | Q6U736 |
|---|
| Gene | OPN5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 354 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.23
- leukocyte count · score 0.22
- mathematical ability · score 0.15
- low grade glioma · score 0.12
- breast adenocarcinoma · score 0.10
- prostate adenocarcinoma · score 0.10
- chronic lymphocytic leukemia · score 0.06
- pancreatic adenocarcinoma · score 0.04
- Myopia · score 0.04
- myopia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6U736-F1 | alphafold | PREDICTED | 83.96 | — |
Amino-acid sequence (354 residues)
MALNHTALPQ DERLPHYLRD GDPFASKLSW EADLVAGFYL TIIGILSTFG NGYVLYMSSR RKKKLRPAEI MTINLAVCDL GISVVGKPFT IISCFCHRWV FGWIGCRWYG WAGFFFGCGS LITMTAVSLD RYLKICYLSY GVWLKRKHAY ICLAAIWAYA SFWTTMPLVG LGDYVPEPFG TSCTLDWWLA QASVGGQVFI LNILFFCLLL PTAVIVFSYV KIIAKVKSSS KEVAHFDSRI HSSHVLEMKL TKVAMLICAG FLIAWIPYAV VSVWSAFGRP DSIPIQLSVV PTLLAKSAAM YNPIIYQVID YKFACCQTGG LKATKKKSLE GFRLHTVTTV RKSSAVLEIH EEWE
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