About Transmembrane protein 270
Transmembrane protein 270 (TMEM270) is a protein
from Homo sapiens identified by UniProt accession
Q6UE05, 265 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Transmembrane protein 270 |
|---|
| UniProt accession | Q6UE05 |
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| Gene | TMEM270 |
|---|
| Organism | Homo sapiens |
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| Length | 265 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- body height · score 0.35
- hemorrhoid · score 0.29
- pulse pressure measurement · score 0.29
- BMI-adjusted waist circumference · score 0.23
- asthma · score 0.22
- serum alanine aminotransferase measurement · score 0.07
- balding measurement · score 0.07
- joint disease · score 0.05
- CCL24 measurement · score 0.05
- Inguinal hernia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UE05-F1 | alphafold | PREDICTED | 66.05 | — |
Amino-acid sequence (265 residues)
MEALPPVRSS LLGILLQVTR LSVLLVQNRD HLYNFLLLKI NLFNHWVSGL AQEARGSCNW QAHLPLGAAA CPLGQALWAG LALIQVPVWL VLQGPRLMWA GMWGSTKGLG LALLSAWEQL GLSVAIWTDL FLSCLHGLML VALLLVVVTW RVCQKSHCFR LGRQLSKALQ VNCVVRKLLV QLRRLYWWVE TMTALTSWHL AYLITWTTCL ASHLLQAAFE HTTQLAEAQE VEPQEVSGSS LLPSLSASSD SESGTVLPEQ ETPRE
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