About Pre-mRNA 3'-end-processing factor FIP1
Pre-mRNA 3'-end-processing factor FIP1 (FIP1L1) is a protein
from Homo sapiens identified by UniProt accession
Q6UN15, 594 residues long.
MolForge cross-references it against 0 known binders and
221 disease associations.
Target properties
| Protein name | Pre-mRNA 3'-end-processing factor FIP1 |
|---|
| UniProt accession | Q6UN15 |
|---|
| Gene | FIP1L1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 594 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (221)
Diseases linked to this target (Open Targets).
- cancer · score 0.46
- serum alanine aminotransferase measurement · score 0.23
- lean body mass · score 0.23
- heel bone mineral density · score 0.22
- creatinine measurement · score 0.22
- neutrophil count · score 0.22
- acute myeloid leukemia · score 0.19
- fat body mass · score 0.19
- leukocyte count · score 0.19
- lymphoid neoplasm · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UN15-F1 | alphafold | PREDICTED | 55.08 | — |
Amino-acid sequence (594 residues)
MSAGEVERLV SELSGGTGGD EEEEWLYGGP WDVHVHSDLA KDLDENEVER PEEENASANP PSGIEDETAE NGVPKPKVTE TEDDSDSDSD DDEDDVHVTI GDIKTGAPQY GSYGTAPVNL NIKTGGRVYG TTGTKVKGVD LDAPGSINGV PLLEVDLDSF EDKPWRKPGA DLSDYFNYGF NEDTWKAYCE KQKRIRMGLE VIPVTSTTNK ITAEDCTMEV TPGAEIQDGR FNLFKVQQGR TGNSEKETAL PSTKAEFTSP PSLFKTGLPP SRNSTSSQSQ TSTASRKANS SVGKWQDRYG RAESPDLRRL PGAIDVIGQT ITISRVEGRR RANENSNIQV LSERSATEVD NNFSKPPPFF PPGAPPTHLP PPPFLPPPPT VSTAPPLIPP PGFPPPPGAP PPSLIPTIES GHSSGYDSRS ARAFPYGNVA FPHLPGSAPS WPSLVDTSKQ WDYYARREKD RDRERDRDRE RDRDRDRERE RTRERERERD HSPTPSVFNS DEERYRYREY AERGYERHRA SREKEERHRE RRHREKEETR HKSSRSNSRR RHESEEGDSH RRHKHKKSKR SKEGKEAGSE PAPEQESTEA TPAE
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