About Transmembrane protein C16orf54
Transmembrane protein C16orf54 (C16orf54) is a protein
from Homo sapiens identified by UniProt accession
Q6UWD8, 224 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Transmembrane protein C16orf54 |
|---|
| UniProt accession | Q6UWD8 |
|---|
| Gene | C16orf54 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (50)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- neoplasm · score 0.08
- acute myeloid leukemia · score 0.05
- cancer · score 0.05
- chronic lymphocytic leukemia · score 0.03
- Acute hepatic failure · score 0.02
- glioblastoma multiforme · score 0.02
- eosinophil count · score 0.02
- Miyoshi myopathy · score 0.02
- clear cell renal carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UWD8-F1 | alphafold | PREDICTED | 59.88 | — |
Amino-acid sequence (224 residues)
MPLTPEPPSG RVEGPPAWEA APWPSLPCGP CIPIMLVLAT LAALFILTTA VLAERLFRRA LRPDPSHRAP TLVWRPGGEL WIEPMGTARE RSEDWYGSAV PLLTDRAPEP PTQVGTLEAR ATAPPAPSAP NSAPSNLGPQ TVLEVPARST FWGPQPWEGR PPATGLVSWA EPEQRPEASV QFGSPQARRQ RPGSPDPEWG LQPRVTLEQI SAFWKREGRT SVGF
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