About GLIPR1-like protein 1
GLIPR1-like protein 1 (GLIPR1L1) is a protein
from Homo sapiens identified by UniProt accession
Q6UWM5, 242 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | GLIPR1-like protein 1 |
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| UniProt accession | Q6UWM5 |
|---|
| Gene | GLIPR1L1 |
|---|
| Organism | Homo sapiens |
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| Length | 242 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- Male infertility with spermatogenesis disorder due to single gene mutation · score 0.05
- spermatogenic failure 3 · score 0.05
- spermatogenic failure 55 · score 0.05
- urate measurement · score 0.03
- bone density · score 0.03
- cup-to-disc ratio measurement · score 0.03
- intrathoracic organ injury · score 0.03
- DNA methylation · score 0.02
- multiple myeloma · score 0.02
- Abnormal sperm morphology · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UWM5-F1 | alphafold | PREDICTED | 85.30 | — |
Amino-acid sequence (242 residues)
MALKNKFSCL WILGLCLVAT TSSKIPSITD PHFIDNCIEA HNEWRGKVNP PAADMKYMIW DKGLAKMAKA WANQCKFEHN DCLDKSYKCY AAFEYVGENI WLGGIKSFTP RHAITAWYNE TQFYDFDSLS CSRVCGHYTQ LVWANSFYVG CAVAMCPNLG GASTAIFVCN YGPAGNFANM PPYVRGESCS LCSKEEKCVK NLCRTPQLII PNQNPFLKPT GRAPQQTAFN PFSLGFLLLR IF
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