Lactase-like protein (LCTL)

About Lactase-like protein

Lactase-like protein (LCTL) is a protein from Homo sapiens identified by UniProt accession Q6UWM7, 567 residues long. MolForge cross-references it against 0 known binders and 145 disease associations.

Target properties

Protein name	Lactase-like protein
UniProt accession	Q6UWM7
Gene	LCTL
Organism	Homo sapiens
Length	567 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (145)

Diseases linked to this target (Open Targets).

hemoglobin measurement · score 0.30
hematocrit · score 0.30
diastolic blood pressure · score 0.29
platelet count · score 0.27
reticulocyte count · score 0.26
triglyceride measurement · score 0.25
Red cell distribution width · score 0.22
body height · score 0.22
mean corpuscular hemoglobin concentration · score 0.22
mean corpuscular hemoglobin · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UWM7-F1	alphafold	PREDICTED	92.54	—

Amino-acid sequence (567 residues)

MKPVWVATLL WMLLLVPRLG AARKGSPEEA SFYYGTFPLG FSWGVGSSAY QTEGAWDQDG KGPSIWDVFT HSGKGKVLGN ETADVACDGY YKVQEDIILL RELHVNHYRF SLSWPRLLPT GIRAEQVNKK GIEFYSDLID ALLSSNITPI VTLHHWDLPQ LLQVKYGGWQ NVSMANYFRD YANLCFEAFG DRVKHWITFS DPRAMAEKGY ETGHHAPGLK LRGTGLYKAA HHIIKAHAKA WHSYNTTWRS KQQGLVGISL NCDWGEPVDI SNPKDLEAAE RYLQFCLGWF ANPIYAGDYP QVMKDYIGRK SAEQGLEMSR LPVFSLQEKS YIKGTSDFLG LGHFTTRYIT ERNYPSRQGP SYQNDRDLIE LVDPNWPDLG SKWLYSVPWG FRRLLNFAQT QYGDPPIYVM ENGASQKFHC TQLCDEWRIQ YLKGYINEML KAIKDGANIK GYTSWSLLDK FEWEKGYSDR YGFYYVEFND RNKPRYPKAS VQYYKKIIIA NGFPNPREVE SWYLKALETC SINNQMLAAE PLLSHMQMVT EIVVPTVCSL CVLITAVLLM LLLRRQS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards