Dehydrogenase/reductase SDR family member 13 (DHRS13)

About Dehydrogenase/reductase SDR family member 13

Dehydrogenase/reductase SDR family member 13 (DHRS13) is a protein from Homo sapiens identified by UniProt accession Q6UX07, 377 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Dehydrogenase/reductase SDR family member 13
UniProt accession	Q6UX07
Gene	DHRS13
Organism	Homo sapiens
Length	377 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

HbA1c measurement · score 0.18
erythrocyte count · score 0.09
smoking status measurement · score 0.08
smoking initiation · score 0.08
cigarettes per day measurement · score 0.08
language measurement · score 0.06
functional brain measurement · score 0.06
cortical thickness · score 0.06
myeloid white cell count · score 0.05
mathematical ability · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UX07-F1	alphafold	PREDICTED	82.84	—

Amino-acid sequence (377 residues)

MEALLLGAGL LLGAYVLVYY NLVKAPPCGG MGNLRGRTAV VTGANSGIGK MTALELARRG ARVVLACRSQ ERGEAAAFDL RQESGNNEVI FMALDLASLA SVRAFATAFL SSEPRLDILI HNAGISSCGR TREAFNLLLR VNHIGPFLLT HLLLPCLKAC APSRVVVVAS AAHCRGRLDF KRLDRPVVGW RQELRAYADT KLANVLFARE LANQLEATGV TCYAAHPGPV NSELFLRHVP GWLRPLLRPL AWLVLRAPRG GAQTPLYCAL QEGIEPLSGR YFANCHVEEV PPAARDDRAA HRLWEASKRL AGLGPGEDAE PDEDPQSEDS EAPSSLSTPH PEEPTVSQPY PSPQSSPDLS KMTHRIQAKV EPEIQLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards