About Layilin
Layilin (LAYN) is a protein
from Homo sapiens identified by UniProt accession
Q6UX15, 382 residues long.
MolForge cross-references it against 0 known binders and
112 disease associations.
Target properties
| Protein name | Layilin |
|---|
| UniProt accession | Q6UX15 |
|---|
| Gene | LAYN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 382 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (112)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.23
- protein measurement · score 0.19
- asthma · score 0.18
- refractive error measurement · score 0.17
- Eczematoid dermatitis · score 0.15
- allergic disease · score 0.14
- allergic rhinitis · score 0.14
- mean corpuscular hemoglobin concentration · score 0.13
- seasonal allergic rhinitis · score 0.13
- diet measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UX15-F1 | alphafold | PREDICTED | 68.53 | — |
Amino-acid sequence (382 residues)
MRPGTALQAV LLAVLLVGLR AATGRLLSAS DLDLRGGQPV CRGGTQRPCY KVIYFHDTSR RLNFEEAKEA CRRDGGQLVS IESEDEQKLI EKFIENLLPS DGDFWIGLRR REEKQSNSTA CQDLYAWTDG SISQFRNWYV DEPSCGSEVC VVMYHQPSAP AGIGGPYMFQ WNDDRCNMKN NFICKYSDEK PAVPSREAEG EETELTTPVL PEETQEEDAK KTFKESREAA LNLAYILIPS IPLLLLLVVT TVVCWVWICR KRKREQPDPS TKKQHTIWPS PHQGNSPDLE VYNVIRKQSE ADLAETRPDL KNISFRVCSG EATPDDMSCD YDNMAVNPSE SGFVTLVSVE SGFVTNDIYE FSPDQMGRSK ESGWVENEIY GY
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