ALK and LTK ligand 2 (ALKAL2)

About ALK and LTK ligand 2

ALK and LTK ligand 2 (ALKAL2) is a protein from Homo sapiens identified by UniProt accession Q6UX46, 152 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.

Target properties

Protein name	ALK and LTK ligand 2
UniProt accession	Q6UX46
Gene	ALKAL2
Organism	Homo sapiens
Length	152 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (120)

Diseases linked to this target (Open Targets).

body mass index · score 0.37
body fat percentage · score 0.32
lean body mass · score 0.31
hip circumference · score 0.29
fat body mass · score 0.28
low molecular weight phosphotyrosine protein phosphatase measurement · score 0.26
PHF-tau measurement · score 0.26
waist circumference · score 0.26
body weight · score 0.25
age at menarche · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UX46-F1	alphafold	PREDICTED	70.12	—

Amino-acid sequence (152 residues)

MRGPGHPLLL GLLLVLGAAG RGRGGAEPRE PADGQALLRL VVELVQELRK HHSAEHKGLQ LLGRDCALGR AEAAGLGPSP EQRVEIVPRD LRMKDKFLKH LTGPLYFSPK CSKHFHRLYH NTRDCTIPAY YKRCARLLTR LAVSPVCMED KQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards