Thiol S-methyltransferase TMT1B (TMT1B)

About Thiol S-methyltransferase TMT1B

Thiol S-methyltransferase TMT1B (TMT1B) is a protein from Homo sapiens identified by UniProt accession Q6UX53, 244 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.

Target properties

Protein name	Thiol S-methyltransferase TMT1B
UniProt accession	Q6UX53
Gene	TMT1B
Organism	Homo sapiens
Length	244 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UX53-F1	alphafold	PREDICTED	94.74	—

Amino-acid sequence (244 residues)

MDILVPLLQL LVLLLTLPLH LMALLGCWQP LCKSYFPYLM AVLTPKSNRK MESKKRELFS QIKGLTGASG KVALLELGCG TGANFQFYPP GCRVTCLDPN PHFEKFLTKS MAENRHLQYE RFVVAPGEDM RQLADGSMDV VVCTLVLCSV QSPRKVLQEV RRVLRPGGVL FFWEHVAEPY GSWAFMWQQV FEPTWKHIGD GCCLTRETWK DLENAQFSEI QMERQPPPLK WLPVGPHIMG KAVK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards