DNA damage-regulated autophagy modulator protein 2 (DRAM2)

About DNA damage-regulated autophagy modulator protein 2

DNA damage-regulated autophagy modulator protein 2 (DRAM2) is a protein from Homo sapiens identified by UniProt accession Q6UX65, 266 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.

Target properties

Protein name	DNA damage-regulated autophagy modulator protein 2
UniProt accession	Q6UX65
Gene	DRAM2
Organism	Homo sapiens
Length	266 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UX65-F1	alphafold	PREDICTED	91.63	—

Amino-acid sequence (266 residues)

MWWFQQGLSF LPSALVIWTS AAFIFSYITA VTLHHIDPAL PYISDTGTVA PEKCLFGAML NIAAVLCIAT IYVRYKQVHA LSPEENVIIK LNKAGLVLGI LSCLGLSIVA NFQKTTLFAA HVSGAVLTFG MGSLYMFVQT ILSYQMQPKI HGKQVFWIRL LLVIWCGVSA LSMLTCSSVL HSGNFGTDLE QKLHWNPEDK GYVLHMITTA AEWSMSFSFF GFFLTYIRDF QKISLRVEAN LHGLTLYDTA PCPINNERTR LLSRDI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards