About UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 (B3GNT9) is a protein
from Homo sapiens identified by UniProt accession
Q6UX72, 402 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 |
|---|
| UniProt accession | Q6UX72 |
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| Gene | B3GNT9 |
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| Organism | Homo sapiens |
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| Length | 402 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- glioblastoma · score 0.07
- monocyte count · score 0.07
- myeloid white cell count · score 0.04
- mean corpuscular hemoglobin concentration · score 0.03
- lymphocyte count · score 0.02
- hair shape measurement · score 0.02
- Myopia · score 0.02
- age at onset · score 0.02
- neoplasm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UX72-F1 | alphafold | PREDICTED | 82.08 | — |
Amino-acid sequence (402 residues)
MRRRLRLRRD ALLTLLLGAS LGLLLYAQRD GAAPTASAPR GRGRAAPRPT PGPRAFQLPD AGAAPPAYEG DTPAPPTPTG PFDFARYLRA KDQRRFPLLI NQPHKCRGDG APGGRPDLLI AVKSVAEDFE RRQAVRQTWG AEGRVQGALV RRVFLLGVPR GAGSGGADEV GEGARTHWRA LLRAESLAYA DILLWAFDDT FFNLTLKEIH FLAWASAFCP DVRFVFKGDA DVFVNVGNLL EFLAPRDPAQ DLLAGDVIVH ARPIRTRASK YYIPEAVYGL PAYPAYAGGG GFVLSGATLH RLAGACAQVE LFPIDDVFLG MCLQRLRLTP EPHPAFRTFG IPQPSAAPHL STFDPCFYRE LVVVHGLSAA DIWLMWRLLH GPHGPACAHP QPVAAGPFQW DS
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