UPF0764 protein C16orf89 (C16orf89)

About UPF0764 protein C16orf89

UPF0764 protein C16orf89 (C16orf89) is a protein from Homo sapiens identified by UniProt accession Q6UX73, 402 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	UPF0764 protein C16orf89
UniProt accession	Q6UX73
Gene	C16orf89
Organism	Homo sapiens
Length	402 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurofibrillary tangles measurement · score 0.10
22q11.2 deletion syndrome · score 0.05
gastric carcinoma · score 0.04
8p23.1 microdeletion syndrome · score 0.04
attention deficit hyperactivity disorder · score 0.04
hypoparathyroidism, familial isolated, 2 · score 0.04
Barrett's esophagus · score 0.03
dilated cardiomyopathy 1I · score 0.03
Primary hypomagnesemia with secondary hypocalcemia · score 0.03
blood protein measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UX73-F1	alphafold	PREDICTED	71.06	—

Amino-acid sequence (402 residues)

MASLGLLLLL LLTALPPLWS SSLPGLDTAE SKATIADLIL SALERATVFL EQRLPEINLD GMVGVRVLEE QLKSVREKWA QEPLLQPLSL RVGMLGEKLE AAIQRSLHYL KLSDPKYLRE FQLTLQPGFW KLPHAWIHTD ASLVYPTFGP QDSFSEERSD VCLVQLLGTG TDSSEPCGLS DLCRSLMTKP GCSGYCLSHQ LLFFLWARMR GCTQGPLQQS QDYINLFCAN MMDLNRRAEA IGYAYPTRDI FMENIMFCGM GGFSDFYKLR WLEAILSWQK QQEGCFGEPD AEDEELSKAI QYQQHFSRRV KRREKQFPDS RSVAQAGVQW RNLGSLQPLP PGFKQFSCLI LPSSWDYRSV PPYLANFYIF LVETGFHHVA HAGLELLISR DPPTSGSQSV GL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards