Probable palmitoyltransferase ZDHHC24 (ZDHHC24)

About Probable palmitoyltransferase ZDHHC24

Probable palmitoyltransferase ZDHHC24 (ZDHHC24) is a protein from Homo sapiens identified by UniProt accession Q6UX98, 284 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Probable palmitoyltransferase ZDHHC24
UniProt accession	Q6UX98
Gene	ZDHHC24
Organism	Homo sapiens
Length	284 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

Bardet-Biedl syndrome · score 0.57
Bardet-Biedl syndrome 1 · score 0.57
Retinal dystrophy · score 0.52
retinitis pigmentosa · score 0.52
genetic disorder · score 0.50
Usher syndrome · score 0.33
apolipoprotein B measurement · score 0.26
low density lipoprotein cholesterol measurement · score 0.19
total cholesterol measurement · score 0.17
hematocrit · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UX98-F1	alphafold	PREDICTED	89.08	—

Amino-acid sequence (284 residues)

MGQPWAAGST DGAPAQLPLV LTALWAAAVG LELAYVLVLG PGPPPLGPLA RALQLALAAF QLLNLLGNVG LFLRSDPSIR GVMLAGRGLG QGWAYCYQCQ SQVPPRSGHC SACRVCILRR DHHCRLLGRC VGFGNYRPFL CLLLHAAGVL LHVSVLLGPA LSALLRAHTP LHMAALLLLP WLMLLTGRVS LAQFALAFVT DTCVAGALLC GAGLLFHGML LLRGQTTWEW ARGQHSYDLG PCHNLQAALG PRWALVWLWP FLASPLPGDG ITFQTTADVG HTAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards