About Solute carrier family 49 member A3
Solute carrier family 49 member A3 (SLC49A3) is a protein
from Homo sapiens identified by UniProt accession
Q6UXD7, 560 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Solute carrier family 49 member A3 |
|---|
| UniProt accession | Q6UXD7 |
|---|
| Gene | SLC49A3 |
|---|
| Organism | Homo sapiens |
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| Length | 560 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- myeloid white cell count · score 0.05
- neutrophil count · score 0.05
- leukocyte count · score 0.04
- granulocyte count · score 0.04
- appendicular lean mass · score 0.04
- lymphocyte percentage of leukocytes · score 0.03
- monocyte percentage of leukocytes · score 0.03
- neutrophil percentage of leukocytes · score 0.03
- eosinophil percentage of leukocytes · score 0.02
- sum of neutrophil and eosinophil counts · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UXD7-F1 | alphafold | PREDICTED | 74.84 | — |
Amino-acid sequence (560 residues)
MAGPTEAETG LAEPRALCAQ RGHRTYARRW VFLLAISLLN CSNATLWLSF APVADVIAED LVLSMEQINW LSLVYLVVST PFGVAAIWIL DSVGLRAATI LGAWLNFAGS VLRMVPCMVV GTQNPFAFLM GGQSLCALAQ SLVIFSPAKL AALWFPEHQR ATANMLATMS NPLGVLVANV LSPVLVKKGE DIPLMLGVYT IPAGVVCLLS TICLWESVPP TPPSAGAASS TSEKFLDGLK LQLMWNKAYV ILAVCLGGMI GISASFSALL EQILCASGHS SGFSGLCGAL FITFGILGAL ALGPYVDRTK HFTEATKIGL CLFSLACVPF ALVSQLQGQT LALAATCSLL GLFGFSVGPV AMELAVECSF PVGEGAATGM IFVLGQAEGI LIMLAMTALT VRRSEPSLST CQQGEDPLDW TVSLLLMAGL CTFFSCILAV FFHTPYRRLQ AESGEPPSTR NAVGGADSGP GVDRGGAGRA GVLGPSTATP ECTARGASLE DPRGPGSPHP ACHRATPRAQ GPAATDAPSR PGRLAGRVQA SRFIDPAGSH SSFSSPWVIT
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