Butyrophilin-like protein 9 (BTNL9)

About Butyrophilin-like protein 9

Butyrophilin-like protein 9 (BTNL9) is a protein from Homo sapiens identified by UniProt accession Q6UXG8, 535 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	Butyrophilin-like protein 9
UniProt accession	Q6UXG8
Gene	BTNL9
Organism	Homo sapiens
Length	535 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (60)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.24
lipoprotein measurement · score 0.21
high density lipoprotein cholesterol measurement · score 0.14
cutaneous melanoma · score 0.12
lung adenocarcinoma · score 0.08
ulnar-mammary syndrome · score 0.07
Pneumothorax · score 0.06
neoplasm · score 0.05
non-small cell lung carcinoma · score 0.04
breast carcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXG8-F1	alphafold	PREDICTED	83.71	—

Amino-acid sequence (535 residues)

MVDLSVSPDS LKPVSLTSSL VFLMHLLLLQ PGEPSSEVKV LGPEYPILAL VGEEVEFPCH LWPQLDAQQM EIRWFRSQTF NVVHLYQEQQ ELPGRQMPAF RNRTKLVKDD IAYGSVVLQL HSIIPSDKGT YGCRFHSDNF SGEALWELEV AGLGSDPHLS LEGFKEGGIQ LRLRSSGWYP KPKVQWRDHQ GQCLPPEFEA IVWDAQDLFS LETSVVVRAG ALSNVSVSIQ NLLLSQKKEL VVQIADVFVP GASAWKSAFV ATLPLLLVLA ALALGVLRKQ RRSREKLRKQ AEKRQEKLTA ELEKLQTELD WRRAEGQAEW RAAQKYAVDV TLDPASAHPS LEVSEDGKSV SSRGAPPGPA PGHPQRFSEQ TCALSLERFS AGRHYWEVHV GRRSRWFLGA CLAAVPRAGP ARLSPAAGYW VLGLWNGCEY FVLAPHRVAL TLRVPPRRLG VFLDYEAGEL SFFNVSDGSH IFTFHDTFSG ALCAYFRPRA HDGGEHPDPL TICPLPVRGT GVPEENDSDT WLQPYEPADP ALDWW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards