About Inactive serine protease PAMR1
Inactive serine protease PAMR1 (PAMR1) is a protein
from Homo sapiens identified by UniProt accession
Q6UXH9, 720 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | Inactive serine protease PAMR1 |
|---|
| UniProt accession | Q6UXH9 |
|---|
| Gene | PAMR1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 720 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (45)
Diseases linked to this target (Open Targets).
- body height · score 0.41
- FEV/FVC ratio · score 0.03
- bone density · score 0.03
- breast carcinoma · score 0.03
- Breslow thickness · score 0.03
- heel bone mineral density · score 0.03
- hepatocellular carcinoma · score 0.02
- psoriasis · score 0.02
- cancer · score 0.02
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UXH9-F1 | alphafold | PREDICTED | 77.12 | — |
Amino-acid sequence (720 residues)
MELGCWTQLG LTFLQLLLIS SLPREYTVIN EACPGAEWNI MCRECCEYDQ IECVCPGKRE VVGYTIPCCR NEENECDSCL IHPGCTIFEN CKSCRNGSWG GTLDDFYVKG FYCAECRAGW YGGDCMRCGQ VLRAPKGQIL LESYPLNAHC EWTIHAKPGF VIQLRFVMLS LEFDYMCQYD YVEVRDGDNR DGQIIKRVCG NERPAPIQSI GSSLHVLFHS DGSKNFDGFH AIYEEITACS SSPCFHDGTC VLDKAGSYKC ACLAGYTGQR CENLLEERNC SDPGGPVNGY QKITGGPGLI NGRHAKIGTV VSFFCNNSYV LSGNEKRTCQ QNGEWSGKQP ICIKACREPK ISDLVRRRVL PMQVQSRETP LHQLYSAAFS KQKLQSAPTK KPALPFGDLP MGYQHLHTQL QYECISPFYR RLGSSRRTCL RTGKWSGRAP SCIPICGKIE NITAPKTQGL RWPWQAAIYR RTSGVHDGSL HKGAWFLVCS GALVNERTVV VAAHCVTDLG KVTMIKTADL KVVLGKFYRD DDRDEKTIQS LQISAIILHP NYDPILLDAD IAILKLLDKA RISTRVQPIC LAASRDLSTS FQESHITVAG WNVLADVRSP GFKNDTLRSG VVSVVDSLLC EEQHEDHGIP VSVTDNMFCA SWEPTAPSDI CTAETGGIAA VSFPGRASPE PRWHLMGLVS WSYDKTCSHR LSTAFTKVLP FKDWIERNMK
Explore Inactive serine protease PAMR1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets