Interleukin-20 receptor subunit beta (IL20RB)

About Interleukin-20 receptor subunit beta

Interleukin-20 receptor subunit beta (IL20RB) is a protein from Homo sapiens identified by UniProt accession Q6UXL0, 311 residues long. MolForge cross-references it against 0 known binders and 176 disease associations.

Target properties

Protein name	Interleukin-20 receptor subunit beta
UniProt accession	Q6UXL0
Gene	IL20RB
Organism	Homo sapiens
Length	311 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (176)

Diseases linked to this target (Open Targets).

BMI-adjusted waist circumference · score 0.29
BMI-adjusted hip circumference · score 0.29
neuritic plaque measurement · score 0.27
monocyte count · score 0.25
neutrophil count · score 0.24
sex hormone-binding globulin measurement · score 0.20
platelet count · score 0.20
lymphocyte count · score 0.19
lymphocyte percentage of leukocytes · score 0.19
leukocyte count · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXL0-F1	alphafold	PREDICTED	83.69	—

Amino-acid sequence (311 residues)

MQTFTMVLEE IWTSLFMWFF YALIPCLLTD EVAILPAPQN LSVLSTNMKH LLMWSPVIAP GETVYYSVEY QGEYESLYTS HIWIPSSWCS LTEGPECDVT DDITATVPYN LRVRATLGSQ TSAWSILKHP FNRNSTILTR PGMEITKDGF HLVIELEDLG PQFEFLVAYW RREPGAEEHV KMVRSGGIPV HLETMEPGAA YCVKAQTFVK AIGRYSAFSQ TECVEVQGEA IPLVLALFAF VGFMLILVVV PLFVWKMGRL LQYSCCPVVV LPDTLKITNS PQKLISCRRE EVDACATAVM SPEELLRAWI S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards