Transmembrane protein 92 (TMEM92)

About Transmembrane protein 92

Transmembrane protein 92 (TMEM92) is a protein from Homo sapiens identified by UniProt accession Q6UXU6, 159 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Transmembrane protein 92
UniProt accession	Q6UXU6
Gene	TMEM92
Organism	Homo sapiens
Length	159 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

heel bone mineral density · score 0.34
bone quantitative ultrasound measurement · score 0.31
bone density · score 0.27
Hydrocephalus · score 0.26
Cerebellar atrophy · score 0.26
Global developmental delay · score 0.26
gonorrhea · score 0.06
Barrett's esophagus · score 0.05
esophageal adenocarcinoma · score 0.03
neoplasm · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXU6-F1	alphafold	PREDICTED	67.19	—

Amino-acid sequence (159 residues)

MSQAWVPGLA PTLLFSLLAG PQKIAAKCGL ILACPKGFKC CGDSCCQENE LFPGPVRIFV IIFLVILSVF CICGLAKCFC RNCREPEPDS PVDCRGPLEL PSIIPPERVR VSLSAPPPPY SEVILKPSLG PTPTEPPPPY SFRPEEYTGD QRGIDNPAF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards