About CMRF35-like molecule 5
CMRF35-like molecule 5 (CD300LD) is a protein
from Homo sapiens identified by UniProt accession
Q6UXZ3, 194 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | CMRF35-like molecule 5 |
|---|
| UniProt accession | Q6UXZ3 |
|---|
| Gene | CD300LD |
|---|
| Organism | Homo sapiens |
|---|
| Length | 194 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- monocyte percentage of leukocytes · score 0.27
- monocyte count · score 0.16
- isolated asymptomatic elevation of creatine phosphokinase · score 0.08
- blood protein measurement · score 0.06
- pentosuria · score 0.06
- neoplasm · score 0.05
- Familial exudative vitreoretinopathy · score 0.04
- neutropenia, severe congenital, 1, autosomal dominant · score 0.04
- Familial drusen · score 0.04
- retinitis pigmentosa and erythrocytic microcytosis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6UXZ3-F1 | alphafold | PREDICTED | 80.39 | — |
Amino-acid sequence (194 residues)
MWLSPSLLLL ILPGYSIAAK ITGPTTVNGS EQGSLTVQCA YGSGWETYLK WRCQGADWNY CNILVKTNGS EQEVKKNRVS IRDNQKNHVF TVTMENLKRD DADSYWCGTE RPGIDLGVKV QVTINPGTQT AVSEWTTTTA SLAFTAAATQ KTSSPLTRSP LKSTHFLFLF LLELPLLLSM LGTVLWVNRP QRRS
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