Repetin (RPTN)

Homo sapiens — UniProt Q6XPR3

Gene: RPTNHomo sapiensSwissProt reviewed

About Repetin

Repetin (RPTN) is a protein from Homo sapiens identified by UniProt accession Q6XPR3, 784 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein nameRepetin
UniProt accessionQ6XPR3
GeneRPTN
OrganismHomo sapiens
Length784 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (40)

Diseases linked to this target (Open Targets).

  • glioblastoma multiforme · score 0.23
  • breast adenocarcinoma · score 0.22
  • prostate adenocarcinoma · score 0.21
  • thyroid gland adenocarcinoma · score 0.19
  • head and neck squamous cell carcinoma · score 0.19
  • clear cell renal carcinoma · score 0.18
  • esophageal cancer · score 0.17
  • gastric adenocarcinoma · score 0.16
  • neuroblastoma · score 0.13
  • urinary bladder cancer · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6XPR3-F1alphafoldPREDICTED42.24—

Amino-acid sequence (784 residues)

MAQLLNSILS VIDVFHKYAK GNGDCALLCK EELKQLLLAE FGDILQRPND PETVETILNL LDQDRDGHID FHEYLLLVFQ LVQACYHKLD NKSHGGRTSQ QERGQEGAQD CKFPGNTGRQ HRQRHEEERQ NSHHSQPERQ DGDSHHGQPE RQDRDSHHGQ SEKQDRDSHH SQPERQDRDS HHNQSERQDK DFSFDQSERQ SQDSSSGKKV SHKSTSGQAK WQGHIFALNR CEKPIQDSHY GQSERHTQQS ETLGQASHFN QTNQQKSGSY CGQSERLGQE LGCGQTDRQG QSSHYGQTDR QDQSYHYGQT DRQGQSSHYS QTDRQGQSSH YSQPDRQGQS SHYGQMDRKG QCYHYDQTNR QGQGSHYSQP NRQGQSSHYG QPDTQDQSSH YGQTDRQDQS SHYGQTERQG QSSHYSQMDR QGQGSHYGQT DRQGQSSHYG QPDRQGQNSH YGQTDRQGQS SHYGQTDRQG QSSHYSQPDK QGQSSHYGKI DRQDQSYHYG QPDGQGQSSH YGQTDRQGQS FHYGQPDRQG QSSHYSQMDR QGQSSHYGQT DRQGQSSHYG QTDRQGQSYH YGQTDRQGQS SHYIQSQTGE IQGQNKYFQG TEGTRKASYV EQSGRSGRLS QQTPGQEGYQ NQGQGFQSRD SQQNGHQVWE PEEDSQHHQH KLLAQIQQER PLCHKGRDWQ SCSSEQGHRQ AQTRQSHGEG LSHWAEEEQG HQTWDRHSHE SQEGPCGTQD RRTHKDEQNH QRRDRQTHEH EQSHQRRDRQ THEDKQNRQR RDRQTHEDEQ NHQR

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Quick facts

UniProtQ6XPR3
GeneRPTN
OrganismHomo sapiens
Length784
Binders0
Diseases40
View on UniProt