About Scavenger receptor class A member 5
Scavenger receptor class A member 5 (SCARA5) is a protein
from Homo sapiens identified by UniProt accession
Q6ZMJ2, 495 residues long.
MolForge cross-references it against 0 known binders and
160 disease associations.
Target properties
| Protein name | Scavenger receptor class A member 5 |
|---|
| UniProt accession | Q6ZMJ2 |
|---|
| Gene | SCARA5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 495 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (160)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.48
- neurodegenerative disease · score 0.39
- von Willebrand factor measurement · score 0.38
- factor VIII measurement · score 0.38
- cholesteryl ester transfer protein measurement · score 0.37
- squamous cell lung carcinoma · score 0.23
- head and neck squamous cell carcinoma · score 0.19
- lung adenocarcinoma · score 0.19
- glioblastoma multiforme · score 0.17
- esophageal cancer · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZMJ2-F1 | alphafold | PREDICTED | 71.49 | — |
Amino-acid sequence (495 residues)
MENKAMYLHT VSDCDTSSIC EDSFDGRSLS KLNLCEDGPC HKRRASICCT QLGSLSALKH AVLGLYLLVF LILVGIFILA VSRPRSSPDD LKALTRNVNR LNESFRDLQL RLLQAPLQAD LTEQVWKVQD ALQNQSDSLL ALAGAVQRLE GALWGLQAQA VQTEQAVALL RDRTGQQSDT AQLELYQLQV ESNSSQLLLR RHAGLLDGLA RRVGILGEEL ADVGGVLRGL NHSLSYDVAL HRTRLQDLRV LVSNASEDTR RLRLAHVGME LQLKQELAML NAVTEDLRLK DWEHSIALRN ISLAKGPPGP KGDQGDEGKE GRPGIPGLPG LRGLPGERGT PGLPGPKGDD GKLGATGPMG MRGFKGDRGP KGEKGEKGDR AGDASGVEAP MMIRLVNGSG PHEGRVEVYH DRRWGTVCDD GWDKKDGDVV CRMLGFRGVE EVYRTARFGQ GTGRIWMDDV ACKGTEETIF RCSFSKWGVT NCGHAEDASV TCNRH
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