Zinc finger protein 852 (ZNF852)

About Zinc finger protein 852

Zinc finger protein 852 (ZNF852) is a protein from Homo sapiens identified by UniProt accession Q6ZMS4, 543 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	Zinc finger protein 852
UniProt accession	Q6ZMS4
Gene	ZNF852
Organism	Homo sapiens
Length	543 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (39)

Diseases linked to this target (Open Targets).

urate measurement · score 0.09
depressive symptom measurement · score 0.05
cystatin C measurement · score 0.04
body fat percentage · score 0.04
C-reactive protein measurement · score 0.04
immunodeficiency 75 · score 0.04
gastroesophageal reflux disease · score 0.04
autoinflammation with episodic fever and lymphadenopathy · score 0.04
glycoprotein storage disease · score 0.04
lean body mass · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6ZMS4-F1	alphafold	PREDICTED	70.36	—

Amino-acid sequence (543 residues)

MVRPQDTVAY EDLSEDYTQK KWKGLALSQR ALHWNMMLEN DRSMASLGRN MMESSELTPK QEIFKGSESS NSTSGGLFGV VPGGTETGDV CEDTFKELEG QPSNEEGSRL ESDFLEIIDE DKKKSTKDRY EEYKEVEEHP PLSSSPVEHE GVLKGQKSYR CDECGKAFYW SSHLIGHRRI HTGEKPYECN ECGKTFRQTS QLIVHLRTHT GEKPYECSEC GKAYRHSSHL IQHQRLHNGE KPYKCNECAK AFNQSSKLFD HQRTHTGEKP YECKECGAAF SRSKNLVRHQ FLHTGKKPYK CNECGRAFCS NRNLIDHQRT HTGEKPYKCN ECGKAFSRSK CLIRHQSLHT GEKPYKCSEC GKAFNQISQL VEHERIHTGE KPFKCSECGK AFGLSKCLIR HQRLHTSEKP YKCNECGKSF NQNSYLIIHQ RIHTGEKPYE CNECGKVFSY NSSLMVHQRT HTGEKPYKCN SCGKAFSDSS QLTVHQRVHT GEKNLMNVLS VGKPLVSVPL LITTSELMLE RSPQVWLGHL LKAWFSETDS KDL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards