Zinc finger protein 783 (ZNF783)

About Zinc finger protein 783

Zinc finger protein 783 (ZNF783) is a protein from Homo sapiens identified by UniProt accession Q6ZMS7, 546 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Zinc finger protein 783
UniProt accession	Q6ZMS7
Gene	ZNF783
Organism	Homo sapiens
Length	546 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

heel bone mineral density · score 0.35
birth weight · score 0.26
basophil percentage of granulocytes · score 0.16
neutrophil count · score 0.13
basophil percentage of leukocytes · score 0.08
pancreatic adenocarcinoma · score 0.04
neoplasm · score 0.01
hepatocellular carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6ZMS7-F1	alphafold	PREDICTED	56.83	—

Amino-acid sequence (546 residues)

MAEAAPARDP ETDKHTEDQS PSTPLPQPAA EKNSYLYSTE ITLWTVVAAI QALEKKVDSC LTRLLTLEGR TGTAEKKLAD CEKTAVEFGN QLEGKWAVLG TLLQEYGLLQ RRLENVENLL RNRNFWILRL PPGSKGEAPK VPVTFDDVAV YFSELEWGKL EDWQKELYKH VMRGNYETLV SLDYAISKPD ILTRIERGEE PCLDRWGQEK GNEVEVGRPR MMGTGLPPYP EHLTSPLSPA QEELKEGQAP KQQQDSEARV APAGPEAGGG VAIKTEAQSE DEMTPERLFL GVSRGQTECR IPRGPRNRPG GPSRHQAQGM PRVRAGEPRP PGASGETPRV LSRRRQRAFP CPDCGQSFRL KINLTIHQRT HVEEGRQEAP GRSPTSCGDS QAMLEPGEVV VPGPVIRWLP EEPEGRRSVA GGRALVGRRP AASKMYHCSE CLRFFQQRKS LLLHQRLHTG NGQGWPACPY CGKAFRRPSD LFRHQRIHTG ERPYQCPQCG RTFNRNHHLA VHMQTHARGQ VGPHFPAAPA RHGSLPLPWP SRKEEG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards