About Zinc finger protein 497
Zinc finger protein 497 (ZNF497) is a protein
from Homo sapiens identified by UniProt accession
Q6ZNH5, 498 residues long.
MolForge cross-references it against 0 known binders and
3 disease associations.
Target properties
| Protein name | Zinc finger protein 497 |
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| UniProt accession | Q6ZNH5 |
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| Gene | ZNF497 |
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| Organism | Homo sapiens |
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| Length | 498 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (3)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- COVID-19 · score 0.01
- ulnar-mammary syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZNH5-F1 | alphafold | PREDICTED | 77.92 | — |
Amino-acid sequence (498 residues)
MESPRGWTLQ VAPEEGQVLC NVKTATRGLS EGAVSGGWGA WENSTEVPRE AGDGQRQQAT LGAADEQGGP GRELGPADGG RDGAGPRSEP ADRALRPSPL PEEPGCRCGE CGKAFSQGSY LLQHRRVHTG EKPYTCPECG KAFAWSSNLS QHQRIHSGEK PYACRECGKA FRAHSQLIHH QETHSGLKPF RCPDCGKSFG RSTTLVQHRR THTGEKPYEC PECGKAFSWN SNFLEHRRVH TGARPHACRD CGKAFSQSSN LAEHLKIHAG ARPHACPDCG KAFVRVAGLR QHRRTHSSEK PFPCAECGKA FRESSQLLQH QRTHTGERPF ECAECGQAFV MGSYLAEHRR VHTGEKPHAC AQCGKAFSQR SNLLSHRRTH SGAKPFACAD CGKAFRGSSG LAHHRLSHTG ERPFACAECG KAFRGSSELR QHQRLHSGER PFVCAHCSKA FVRKSELLSH RRTHTGERPY ACGECGKPFS HRCNLNEHQK RHGGRAAP
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