About Uncharacterized protein C15orf39
Uncharacterized protein C15orf39 (C15orf39) is a protein
from Homo sapiens identified by UniProt accession
Q6ZRI6, 1047 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Uncharacterized protein C15orf39 |
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| UniProt accession | Q6ZRI6 |
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| Gene | C15orf39 |
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| Organism | Homo sapiens |
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| Length | 1047 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- mean reticulocyte volume · score 0.30
- testosterone measurement · score 0.15
- hemoglobin measurement · score 0.15
- high density lipoprotein cholesterol measurement · score 0.13
- mean corpuscular volume · score 0.11
- heel bone mineral density · score 0.07
- hematocrit · score 0.06
- leukocyte count · score 0.05
- systemic scleroderma · score 0.03
- systemic lupus erythematosus · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZRI6-F1 | alphafold | PREDICTED | 48.40 | — |
Amino-acid sequence (1047 residues)
MAEKRPLRTL GPVMYGKLPR LETDSGLEHS LPHSVGNQDP CTYKGSYFSC PMAGTPKAES EQLASWTPYP PLYSTGMAGP PLQADNLLTN CLFYRSPAEG PEKMQDSSPV ELLPFSPQAH SYPGPPLAAP KPVYRNPLCY GLSTCLGEGA VKRPLDVDWT LATGPLLPSA DPPCSLAPAP SKGQTLDGTF LRGVPAEGSS KDSSGSFSPC QPFLEKYQTI HSTGFLASRY TGPYPRNSKQ AMSEGPSSPW TQLAQPLGPP CQDTGPTHYP PPHHPPPHPP QALPCPPACR HPEKQGSYSP ALPLQPLGGH KGTGYQAGGL GSPYLRQQAA QAPYIPPLGL DAYPYPSAPL PAPSPGLKLE PPLTPRCPLD FAPQTLSFPY ARDDLSLYGA SPGLGGTPPS QNNVRAVPQP GAFQRACQPL PASQPCSEPV RPAQEAEEKT WLPSCRKEKL QPRLSEHSGP PIVIRDSPVP CTPPALPPCA RECQSLPQKE GARPPSSPPM PVIDNVFSLA PYRDYLDVPA PEATTEPDSA TAEPDSAPAT SEGQDKGCRG TLPAQEGPSG SKPLRGSLKE EVALDLSVRK PTAEASPVKA SRSVEHAKPT AAMDVPDVGN MVSDLPGLKK IDTEAPGLPG VPVTTDAMPR TNFHSSVAFM FRKFKILRPA PLPAAVVPST PTSAPAPTQP APTPTSGPIG LRILAQQPLS VTCFSLALPS PPAVAVASPA PAPAPSPAPA RAQAPASARD PAPAPAPVAG PAPASTSAPG DSLEQHFTGL HASLCDAISG SVAHSPPEKL REWLETAGPW GQAAWQDCQG VQGLLAKLLS QLQRFDRTHR CPFPHVVRAG AIFVPIHLVK ERLFPRLPPA SVDHVLQEHR VELRPTTLSE ERALRELALP GCTSRMLKLL ALRQLPDIYP DLLGLQWRDC VRRQLGDFDT EAGAVSSSEP TVARGEPESL ALAQKSPAPK VRKPGRKPPT PGPEKAEAAA GEESCGASPT PATSASPPGP TLKARFRSLL ETAWLNGLAL PTWGHKSSRP DQPSPCPQLL DSQSHHL
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