About Proline-rich protein 23C
Proline-rich protein 23C (PRR23C) is a protein
from Homo sapiens identified by UniProt accession
Q6ZRP0, 262 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Proline-rich protein 23C |
|---|
| UniProt accession | Q6ZRP0 |
|---|
| Gene | PRR23C |
|---|
| Organism | Homo sapiens |
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| Length | 262 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- Keloid · score 0.09
- insulin like growth factor measurement · score 0.07
- IGF-1 measurement · score 0.07
- 3-hydroxypropylmercapturic acid measurement · score 0.06
- facial morphology measurement · score 0.04
- eye morphology measurement · score 0.03
- body mass index · score 0.03
- obesity · score 0.03
- cortical surface area measurement · score 0.03
- brain measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZRP0-F1 | alphafold | PREDICTED | 58.22 | — |
Amino-acid sequence (262 residues)
MGSRPCSPSA CLAPWWGQQP GGPGPAKRSR LEEPAGPESR AAPSPEDPAG TPAVDALTSM VVLDAGCALR VPLEDVDLVL ELAPMSVLRV SLGGHTLIVI PEVLLSSVDE CSGAQGDWSA GLEVDVFLGA HGEDVVVEQE VCASVPEIAA EEEAYEEDAD SEFPELWMDS AAGSAAGLYP SARSMFSPYR EGPIRGPCAL APNPSSERRS PRPIFDLEFH LLEPVPSSPL QPLPPSPSPG PHARPELPER PPCKVRRRLF QE
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