About Proline-rich protein 23B
Proline-rich protein 23B (PRR23B) is a protein
from Homo sapiens identified by UniProt accession
Q6ZRT6, 265 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Proline-rich protein 23B |
|---|
| UniProt accession | Q6ZRT6 |
|---|
| Gene | PRR23B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 265 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- Keloid · score 0.15
- androgenetic alopecia · score 0.10
- alopecia · score 0.10
- cortical thickness · score 0.09
- brain measurement · score 0.09
- cortical surface area measurement · score 0.09
- balding measurement · score 0.09
- neuroimaging measurement · score 0.07
- 3-hydroxypropylmercapturic acid measurement · score 0.05
- hair shape measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZRT6-F1 | alphafold | PREDICTED | 55.80 | — |
Amino-acid sequence (265 residues)
MVSRPRSPSA FPAPWWGQQP GGPGPAKRLR LEEPAGPEPR AAPSLEDPAG DPAVDALTSI VVLAAGCALR VPLDDVDLVL EPAPTSILRV SLGGHTLILI PEVLLSSVDE RSGAQHDSSA GLEVDVFLGA VREDVVVELE FCASVPEIAA QEEAYEEDAD PEFPELRMDS PTGSAAGLYP SSRSMFIPYR EGPIPEPCAL APNPSSERRS PRPIFDLEFR LLEPVPSSPL QPLPPSPCVG SPGPHARSPL PERPPCKARR RLFQA
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