RNA-binding protein with multiple splicing 2 (RBPMS2)

About RNA-binding protein with multiple splicing 2

RNA-binding protein with multiple splicing 2 (RBPMS2) is a protein from Homo sapiens identified by UniProt accession Q6ZRY4, 209 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.

Target properties

Protein name	RNA-binding protein with multiple splicing 2
UniProt accession	Q6ZRY4
Gene	RBPMS2
Organism	Homo sapiens
Length	209 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (105)

Diseases linked to this target (Open Targets).

platelet count · score 0.26
platelet crit · score 0.18
electrocardiography · score 0.17
IGF-1 measurement · score 0.17
coronary artery disease · score 0.16
mathematical ability · score 0.10
PR interval · score 0.09
age at menarche · score 0.09
gonorrhea · score 0.08
uncombable hair syndrome · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6ZRY4-F1	alphafold	PREDICTED	68.35	—

Amino-acid sequence (209 residues)

MSNLKPDGEH GGSTGTGSGA GSGGALEEEV RTLFVSGLPV DIKPRELYLL FRPFKGYEGS LIKLTARQPV GFVIFDSRAG AEAAKNALNG IRFDPENPQT LRLEFAKANT KMAKSKLMAT PNPSNVHPAL GAHFIARDPY DLMGAALIPA SPEAWAPYPL YTTELTPAIS HAAFTYPTAT AAAAALHAQV RWYPSSDTTQ QGWKYRQFC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards