Leucine-rich repeat-containing protein 55 (LRRC55)

About Leucine-rich repeat-containing protein 55

Leucine-rich repeat-containing protein 55 (LRRC55) is a protein from Homo sapiens identified by UniProt accession Q6ZSA7, 298 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

Target properties

Protein name	Leucine-rich repeat-containing protein 55
UniProt accession	Q6ZSA7
Gene	LRRC55
Organism	Homo sapiens
Length	298 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (68)

Diseases linked to this target (Open Targets).

high density lipoprotein cholesterol measurement · score 0.35
brain measurement · score 0.20
small bowel Crohn's disease · score 0.15
mathematical ability · score 0.12
subcutaneous tissue infection · score 0.09
skin infection · score 0.09
focal segmental glomerulosclerosis · score 0.08
body mass index · score 0.08
nephrotic syndrome · score 0.08
familial idiopathic steroid-resistant nephrotic syndrome · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6ZSA7-F1	alphafold	PREDICTED	86.53	—

Amino-acid sequence (298 residues)

MGDTWAQLPW PGPPHPAMLL ISLLLAAGLM HSDAGTSCPV LCTCRNQVVD CSSQRLFSVP PDLPMDTRNL SLAHNRITAV PPGYLTCYME LQVLDLHNNS LMELPRGLFL HAKRLAHLDL SYNNFSHVPA DMFQEAHGLV HIDLSHNPWL RRVHPQAFQG LMQLRDLDLS YGGLAFLSLE ALEGLPGLVT LQIGGNPWVC GCTMEPLLKW LRNRIQRCTA DSQLAECRGP PEVEGAPLFS LTEESFKACH LTLTLDDYLF IAFVGFVVSI ASVATNFLLG ITANCCHRWS KASEEEEI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards