About Spermatogenesis-associated protein 31D4
Spermatogenesis-associated protein 31D4 (SPATA31D4) is a protein
from Homo sapiens identified by UniProt accession
Q6ZUB0, 917 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Spermatogenesis-associated protein 31D4 |
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| UniProt accession | Q6ZUB0 |
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| Gene | SPATA31D4 |
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| Organism | Homo sapiens |
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| Length | 917 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (27)
Diseases linked to this target (Open Targets).
- visual perception measurement · score 0.29
- rheumatoid arthritis · score 0.24
- FEV/FVC ratio · score 0.22
- appendicular lean mass · score 0.17
- schizophrenia · score 0.13
- autism spectrum disorder · score 0.07
- drug use measurement · score 0.07
- acroleukopathy, symmetric · score 0.07
- familial generalized lentiginosis · score 0.07
- familial progressive hyperpigmentation · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZUB0-F1 | alphafold | PREDICTED | 45.13 | — |
Amino-acid sequence (917 residues)
MENILCFLNS YTETGLSPDS HCLDIDLNFI CLSGLGLFIL YLFYMVLTLY SSPTEKNNDT QKHQGRARRK RKSVTFKDRK SLQKEAEEER KLHSFLKSFG PPVSCSPLGQ HHDTTLFRRL LCPDPVCRVC NRATADIQRL LSWESLKDAA PSVSPLASSA SGAESSFTLA STPSATTPED LILSSRPKPS PPPPLILSPD LITTLADLFS PSPLRDPLPP QPVSPLDSKF PIDHSPPQQL PFPLLPPHHI ERVEPSLQPE ASLSLNTIFS FGSTLCQDIS QAVNRTDSCA RHHGPPTPSA LPPEDCTVTQ SKSNLTVLKT FPEMLSLGGS GGSSTSAPTT KGIDHSCPAS SEFSWWQPHA KDSFSSNFVP SDFMEELLTL HSSEASLGGH SVANIIQPVN ISFLSHDIPA LLERQVKRRG DFLMWKENGK KPGSFPTQLR PNYQLNSSRN MLTSTAVKHD LAESFPFWAS KGKLEWQHIH QQPPYSKCFE DHLEQKYVQL FWGLPSLHSE SLHPTVFVQH GRSSMFVFFN GITNTSMSHE SPVLPPPQPL FLPSTQPLPL PQTLPRGQSL HLTQVKSLAQ PQSPFPALPP SPLFLIRVCG VCFHRPQNEA RSLMPSEINH LEWNVLQKVQ ESVWGLPSVV QKSQEDFCPP APNPVLVRKS FKVHVPISII PGDFPLSSEV RKKLEQHIRK RLIQRRWGLP RRIHESLSLL RPQNKISELS VSESIHGPLN ISLVEGQRCN VLKKSASSFP RSFHERSSNM LSMENVGNYQ GCSQETAPKN HLLHDPETSS DEDLRSNSER DLGTHMMHLS GNDSGVRLGQ KQLENALTVH LSKKFEEINE GRMPGTVHSS WHSVKQTICL PEKSHSQIKH RNLAALVSED HGVDTSQEMS FLSSNKQKML EAHIKSFHMK PILNLSI
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