About Spermatogenesis-associated protein 31E1
Spermatogenesis-associated protein 31E1 (SPATA31E1) is a protein
from Homo sapiens identified by UniProt accession
Q6ZUB1, 1445 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Spermatogenesis-associated protein 31E1 |
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| UniProt accession | Q6ZUB1 |
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| Gene | SPATA31E1 |
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| Organism | Homo sapiens |
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| Length | 1445 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (14)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.27
- metabolite measurement · score 0.16
- genetic disorder · score 0.12
- osteoarthritis · score 0.04
- pulse pressure measurement · score 0.03
- protein measurement · score 0.03
- breast carcinoma · score 0.02
- gut microbiome measurement · score 0.02
- colorectal adenocarcinoma · score 0.01
- ulcerative colitis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZUB1-F1 | alphafold | PREDICTED | 38.64 | — |
Amino-acid sequence (1445 residues)
MGNLVIPLGK GRAGRVESGQ RIPPPAPRPS VECTGDDIAL QMEKMLFPLK SPSATWLSPS STPWMMDFIL TSVCGLVLLF LLLLYVHSDP PSPPPGRKRS SREPQRERSG RSRSRKISAL KACRILLREL EETRDLNYLL ESHLRKLAGE GSSHLPLGGD PLGDVCKPVP AKAHQPHGKC MQDPSPASLS PPAPPAPLAS TLSPGPMTFS EPFGPHSTLS ASGPPEPLLP LKCPATQPHV VFPPSPQPHG PLASSPPPPD SSLAGLQCGS TTCPVPQSSP LHNQVLPPPT RVISGLGCSS DPIWDLYCWR EAATTWGLST YSHGKSQPRH LPDHTSEASF WGDPTPKHME VGGCTFIHPD VQKLLETLIA KRALMKMWQE KERKRADHPH MTSLGKEWDI TTLNPFWNVS TQPQQLPRPQ QVSDATTVGN HLQQKRSQLF WDLPSLNSES LATTVWVSRN PSSQNAHSVP LDKASTSLPG EPEVEASSQL SQAPPQPHHM AQPQHFTPAW PQSQPPPLAE IQTQAHLSPP VPSLGCSSPP QIRGCGASYP TSQERTQSVI PTGKEYLEWP LKKRPKWKRV LPSLLKKSQA VLSQPTAHLP QERPASWSPK SAPILPGVVT SPELPEHWWQ GRNAIHQEQS CGPPSRLQAS GDLLQPDGEF PGRPQSQAED TQQALLPSQP SDFAGKGRKD VQKTGFRSSG RFSDKGCLGS KLGPDPSRDQ GSGRTSVKAL DEDKEAEGDL RRSWKYQSVS STPRDPDKEH LENKLQIHLA RKVGEIKEGW IPMPVRRSWL MAKCAVPKSD THRKPGKLAS WRGGKAHVNT SQELSFLHPC TQQILEVHLV RFCVRHSWGT DLQSLEPINV WSGEAQAPPF PQSTFTPWAS WVSRVESVPK VPIFLGKRPQ NGPGDNRTTS KSVPTVSGPL AAPPPEQEGV QRPPRGSQSA DTHGRSEAFP TGHKGRGCSQ PPTCSLVGRT WQSRTVLESG KPKPRLEGSM GSEMAGNEAW LESESMSPGD PCSSRALQVL SIGSQWARAE DALQALKVGE KPPTWEVTLG ASVRASSGSV QEDLRSTGAL GTTGNPSASS VCVAQDPEQL HLKAQVVSEI ALIVQVDSEE QLPGRAPGIL LQDGATGLCL PGRHMDMLTA ADRLPTQAPL STSQSVSGKN MTASQGPCAL LWKGGDSPGQ QEPGSPKAKA PQKSQKTLGC ADKGEAHRRP RTGEQGHRSK GPRTSEASGR SHPAQAREIG DKQERKYNQL QLEKGQTPPE SHFQRKISHH PQGLHPRKGG TRWEDVLQKG KPGADAFQSW GSGPPRQFMD CMADKAWTIS RVVGQILVDK LGLQWGRGPS EVNRHKGDFR AQENVPSCCH RGHCHQERSR EMRALACSPK ATPKGHHCPV KNRGIRDRDS SWAPPPREPV SPAGPHHHRP RMASTSGGPH PQLQELMSAQ RCLAS
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