About Coiled-coil domain-containing protein 9B
Coiled-coil domain-containing protein 9B (CCDC9B) is a protein
from Homo sapiens identified by UniProt accession
Q6ZUT6, 534 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 9B |
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| UniProt accession | Q6ZUT6 |
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| Gene | CCDC9B |
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| Organism | Homo sapiens |
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| Length | 534 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (23)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.35
- body weight · score 0.28
- Drugs used in diabetes use measurement · score 0.28
- glucose measurement · score 0.27
- cystatin C measurement · score 0.26
- HbA1c measurement · score 0.17
- hemoglobin A1 measurement · score 0.05
- intelligence · score 0.03
- self reported educational attainment · score 0.03
- cognitive function measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZUT6-F1 | alphafold | PREDICTED | 53.57 | — |
Amino-acid sequence (534 residues)
MISCAEQRSR QGEAGRGPAP VAPAFLPLWL PRGCSGILSV PAVAMHSAGT PRAESPMSRQ EKDAELDRRI VALRKKNQAL LRRYQEIQED RRQAEQGGMA VTTPALLQPD GLTVTISQVP GEKRVVSRNW ARGTCGPRVT NEMLEDEDAE DHGGTFCLGE LVELAVTMEN KAEGKRIVSE KPTRARNQGI EGSPGGRVTR SPPTQVAISS DSARKGSWEP WSRPVGEPPE AGWDYAQWKQ EREQIDLARL ARHRDAQGDW RRPWDLDKAK STLQDCSQLR GEGPARAGSR RGPRSHQKLQ PPPLLPDGKG RGGQASRPSV APATGSKARG KERLTGRARR WDMKEDKEEL EGQEGSQSTR ETPSEEEQAQ KQSGMEQGRL GSAPAASPAL ASPEGPKGES VASTASSVPC SPQEPDLAPL DLSLGGAGIP GPRESGCVLG LRPGAQESPV SWPEGSKQQP LGWSNHQAEL EVQTCPEPQR GAGLPEPGED RSGKSGAQQG LAPRSRPTRG GSQRSRGTAG VRRRTGRPGP AGRC
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