About LHFPL tetraspan subfamily member 2 protein
LHFPL tetraspan subfamily member 2 protein (LHFPL2) is a protein
from Homo sapiens identified by UniProt accession
Q6ZUX7, 228 residues long.
MolForge cross-references it against 0 known binders and
114 disease associations.
Target properties
| Protein name | LHFPL tetraspan subfamily member 2 protein |
|---|
| UniProt accession | Q6ZUX7 |
|---|
| Gene | LHFPL2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (114)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- testosterone measurement · score 0.45
- systolic blood pressure · score 0.36
- macula measurement · score 0.33
- platelet count · score 0.31
- pulse pressure measurement · score 0.30
- birth weight · score 0.29
- platelet component distribution width · score 0.26
- cardiovascular disease · score 0.22
- blood pressure · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZUX7-F1 | alphafold | PREDICTED | 83.34 | — |
Amino-acid sequence (228 residues)
MCHVIVTCRS MLWTLLSIVV AFAELIAFMS ADWLIGKARS RGGVEPAGPG GGSPEPYHPT LGIYARCIRN PGVQHFQRDT LCGPYAESFG EIASGFWQAT AIFLAVGIFI LCMVALVSVF TMCVQSIMKK SIFNVCGLLQ GIAGLFLILG LILYPAGWGC QKAIDYCGHY ASAYKPGDCS LGWAFYTAIG GTVLTFICAV FSAQAEIATS SDKVQEEIEE GKNLICLL
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