About Protein CFAP20DC
Protein CFAP20DC (CFAP20DC) is a protein
from Homo sapiens identified by UniProt accession
Q6ZVT6, 689 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Protein CFAP20DC |
|---|
| UniProt accession | Q6ZVT6 |
|---|
| Gene | CFAP20DC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 689 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.45
- rheumatoid arthritis · score 0.32
- smoking status measurement · score 0.19
- breast carcinoma · score 0.17
- pulmonary arterial hypertension · score 0.08
- dimethylglycine measurement · score 0.05
- transient myeloproliferative syndrome · score 0.04
- neutrophil immunodeficiency syndrome · score 0.04
- hemolytic anemia · score 0.03
- uterine leiomyosarcoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ZVT6-F1 | alphafold | PREDICTED | 53.01 | — |
Amino-acid sequence (689 residues)
MIKRKIWCNL CIDLVAFTSE IFKGAVFQSL DGIVVSANCK LRKIFTLKSK PQDTADKDAV YGVPFSTDEP TDIIPRSCQL MTDVPHVTQL LNMTKLRQTE IKFGGHPLRS AESDQFINRG TSITRNSKNQ DVCHIAFGSK VLGPPPLSGR RNNMKISSET VRSVGSKNNR SCQPSTVEKC VNGTEMSALL IPESEEQGNK ENIHQIKQTV PIHAANLHIM HPHPPQEPSA DKNNNRRRLR LKSTSRERTE TPSGSSSGNN RIEDKASTIL TTVSQQGAEL LNSGTLGPQS PDQSDEWIFP ENADHISYLA SSRQSLLLGD DSCNPSHLWL EASKESEHDQ QAEESQSVPK DIFTFSSRPR SAPHGKTQTM SPEELSFILD LKEDNSVTSR DTQSEDDFYG GDSSEEGNHS IQGSRGPTTG PSELTQLTLE SLLGKAAKRT SKEYLRSAYT EAGATESQDS SMEQIDRNNF EMSLLPTTCL SPTGRRCGSC QKTPEPVIKA KDLSAQQVPA SLNKTSLKEI SGERLSSIPE ASEYDWRNYQ PSQMSESELQ MLASLRWQQN EELEDAGTSH GLSASQVDNC NVSISTSSDD TTTWNSCLPP PVNQGRHYQK EMNPPSPSNP RDWLNMLSPP IVPPSQQPAE QRPDSCESLS VQGEEDLSVE EDEEVLTLLY DPCLNCYFDP QTGKYYELV
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