About Keratin-associated protein 5-5
Keratin-associated protein 5-5 (KRTAP5-5) is a protein
from Homo sapiens identified by UniProt accession
Q701N2, 237 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Keratin-associated protein 5-5 |
|---|
| UniProt accession | Q701N2 |
|---|
| Gene | KRTAP5-5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 237 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- head and neck squamous cell carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- systolic blood pressure · score 0.13
- cathepsin D measurement · score 0.12
- body height · score 0.11
- diastolic blood pressure · score 0.11
- hematocrit · score 0.08
- hemoglobin measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q701N2-F1 | alphafold | PREDICTED | 42.50 | — |
Amino-acid sequence (237 residues)
MGCCGCSGGC GSGCGGRGSG CGGCGSGCGG CGSGCGGCGS GCGGCGGCGS GCAGCGGCGS GCCVPVCCCK PMCCCVPACS CSSCGKGGCG SCGGSKRGCV SCGVSKGACG SCGGSKGGCG SCGGSKGGCG SCGGSKGGCG SCGGSKGGCG SYGCSQSSCC KPCCCSSGCG SSCCQSSCCK PYCCQSSCCK PYCCQSSCCK PCSCFSGCGS SCCQSSCYKP CCCQSSCCVP VCCQCKI
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