About Keratin-associated protein 5-2
Keratin-associated protein 5-2 (KRTAP5-2) is a protein
from Homo sapiens identified by UniProt accession
Q701N4, 177 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Keratin-associated protein 5-2 |
|---|
| UniProt accession | Q701N4 |
|---|
| Gene | KRTAP5-2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 177 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- head and neck squamous cell carcinoma · score 0.18
- prostate carcinoma · score 0.07
- brain volume measurement · score 0.06
- insulin like growth factor measurement · score 0.05
- hematocrit · score 0.04
- neuroimaging measurement · score 0.04
- sphingomyelin measurement · score 0.03
- hemoglobin measurement · score 0.03
- blood protein measurement · score 0.02
- erythrocyte count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q701N4-F1 | alphafold | PREDICTED | 39.43 | — |
Amino-acid sequence (177 residues)
MGCCGCSRGC GSGCGGCGSS CGGCGSGCGG CGSGRGGCGS GCGGCSSSCG GCGSRCYVPV CCCKPVCSWV PACSCTSCGS CGGSKGGCGS CGGSKGGCGS CGGSKGGCGS CGCSQSSCCK PCCCSSGCGS SCCQSSCCKP CCCQSSCCVP VCCQSSCCKP CCCQSNCCVP VCCQCKI
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