About Xin actin-binding repeat-containing protein 1
Xin actin-binding repeat-containing protein 1 (XIRP1) is a protein
from Homo sapiens identified by UniProt accession
Q702N8, 1843 residues long.
MolForge cross-references it against 0 known binders and
238 disease associations.
Target properties
| Protein name | Xin actin-binding repeat-containing protein 1 |
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| UniProt accession | Q702N8 |
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| Gene | XIRP1 |
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| Organism | Homo sapiens |
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| Length | 1843 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
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| AF-Q702N8-F1 | alphafold | PREDICTED | 43.64 | — |
Amino-acid sequence (1843 residues)
MADTQTQVAP TPTMRMATAE DLPLPPPPAL EDLPLPPPKE SFSKFHQQRQ ASELRRLYRH IHPELRKNLA EAVAEDLAEV LGSEEPTEGD VQCMRWIFEN WRLDAIGEHE RPAAKEPVLC GDVQATSRKF EEGSFANSTD QEPTRPQPGG GDVRAARWLF ETKPLDELTG QAKELEATVR EPAASGDVQG TRMLFETRPL DRLGSRPSLQ EQSPLELRSE IQELKGDVKK TVKLFQTEPL CAIQDAEGAI HEVKAACREE IQSNAVRSAR WLFETRPLDA INQDPSQVRV IRGISLEEGA RPDVSATRWI FETQPLDAIR EILVDEKDFQ PSPDLIPPGP DVQQQQHLFE TRALDTLKGD EEAGAEAPPK EEVVPGDVRS TLWLFETKPL DAFRDKVQVG HLQRVDPQDG EGHLSSDSSS ALPFSQSAPQ RDELKGDVKT FKNLFETLPL DSIGQGEVLA HGSPSREEGT DSAGQAQGIG SPVYAMQDSK GRLHALTSVS REQIVGGDVQ GYRWMFETQP LDQLGRSPST IDVVRGITRQ EVVAGDVGTA RWLFETQPLE MIHQREQQER QKEEGKSQGD PQPEAPPKGD VQTIRWLFET CPMSELAEKQ GSEVTDPTAK AEAQSCTWMF KPQPVDRPVG SREQHLQVSQ VPAGERQTDR HVFETEPLQA SGRPCGRRPV RYCSRVEIPS GQVSRQKEVF QALEAGKKEE QEPRVIAGSI PAGSVHKFTW LFENCPMGSL AAESIQGGNL LEEQPMSPSG NRMQESQETA AEGTLRTLHA TPGILHHGGI LMEARGPGEL CLAKYVLSGT GQGHPYIRKE ELVSGELPRI ICQVLRRPDV DQQGLLVQED PTGQLQLKPL RLPTPGSSGN IEDMDPELQQ LLACGLGTSV ARTGLVMQET EQGLVALTAY SLQPRLTSKA SERSSVQLLA SCIDKGDLSG LHSLRWEPPA DPSPVPASEG AQSLHPTESI IHVPPLDPSM GMGHLRASGA TPCPPQAIGK AVPLAGEAAA PAQLQNTEKQ EDSHSGQKGM AVLGKSEGAT TTPPGPGAPD LLAAMQSLRM ATAEAQSLHQ QVLNKHKQGP TPTATSNPIQ DGLRKAGATQ SNIRPGGGSD PRIPAAPRKV SREEQALPRG LPGGWVTIQD GIYTAHPVRT FDPPGGVQLS QREPQSRHRE TALSVQAPRP LQGGPGQSTG PGREEPGGCT QMAWGPPGKA MAEVCPGGLQ AAETTLKTAP LGRHILASGP QAAGASPHPH NAFVPPPPTL PAAVTGPDFP AGAHRAEDSI QQASEPLKDP LLHSHSSPAG QRTPGGSQTK TPKLDPTMPP KKKPQLPPKP AHLTQSHPPQ RLPKPLPLSP SFSSEVGQRE HQRGERDTAI PQPAKVPTTV DQGHIPLARC PSGHSQPSLQ HGLSTTAPRP TKNQATGSNA QSSEPPKLNA LNHDPTSPQW GPGPSGEQPM EGSHQGAPES PDSLQRNQKE LQGLLNQVQA LEKEAASSVD VQALRRLFEA VPQLGGAAPQ APAAHQKPEA SVEQAFGELT RVSTEVAQLK EQTLARLLDI EEAVHKALSS MSSLQPEASA RGHFQGPPKD HSAHKISVTV SSSARPSGSG QEVGGQTAVK NQAKVECHTE AQSQVKIRNH TEARGHTAST APSTRRQETS REYLCPPRVL PSSRDSPSSP TFISIQSATR KPLETPSFKG NPDVSVKSTQ LAQDIGQALL HQKGVQDKTG KKDITQCSVQ PEPAPPSASP LPRGWQKSVL ELQTGPGSSQ HYGAMRTVTE QYEEVDQFGN TVLMSSTTVT EQAEPPRNPG SHLGLHASPL LRQFLHSPAG FSSDLTEAET VQVSCSYSQP AAQ
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