Ubiquitin carboxyl-terminal hydrolase 50 (USP50)

About Ubiquitin carboxyl-terminal hydrolase 50

Ubiquitin carboxyl-terminal hydrolase 50 (USP50) is a protein from Homo sapiens identified by UniProt accession Q70EL3, 339 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein name	Ubiquitin carboxyl-terminal hydrolase 50
UniProt accession	Q70EL3
Gene	USP50
Organism	Homo sapiens
Length	339 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q70EL3-F1	alphafold	PREDICTED	80.81	—

Amino-acid sequence (339 residues)

MTSQPSLPAD DFDIYHVLAE CTDYYDTLPV KEADGNQPHF QGVTGLWNLG NTCCVNAISQ CLCSILPLVE YFLTGKYITA LQKFLLPSDC SEVATAFAYL MTDMWLGDSD CVSPEIFWSA LGNLYPAFTK KMQQDAQEFL ICVLNELHEA LKKYHYSRRR SYEKGSTQRC CRKWITTETS IITQLFEEQL NYSIVCLKCE KCTYKNEVFT VFSLPIPSKY ECSLRDCLQC FFQQDALTWN NEIHCSFCET KQETAVRASI SKAPKIIIFH LKRFDIQGTT KRKLRTDIHY PLTNLDLTPY ICSIFRKYPK YNLCAVVNHF GDLDGGHYTA FCKNSVTQA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards