About MOB kinase activator 2
MOB kinase activator 2 (MOB2) is a protein
from Homo sapiens identified by UniProt accession
Q70IA6, 237 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | MOB kinase activator 2 |
|---|
| UniProt accession | Q70IA6 |
|---|
| Gene | MOB2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 237 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (50)
Diseases linked to this target (Open Targets).
- body height · score 0.28
- prostate carcinoma · score 0.27
- insulin like growth factor measurement · score 0.25
- brain measurement · score 0.21
- heel bone mineral density · score 0.21
- neuroimaging measurement · score 0.20
- white matter microstructure measurement · score 0.20
- chronotype measurement · score 0.19
- body mass index · score 0.12
- body fat percentage · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q70IA6-F1 | alphafold | PREDICTED | 85.01 | — |
Amino-acid sequence (237 residues)
MDWLMGKSKA KPNGKKPAAE ERKAYLEPEH TKARITDFQF KELVVLPREI DLNEWLASNT TTFFHHINLQ YSTISEFCTG ETCQTMAVCN TQYYWYDERG KKVKCTAPQY VDFVMSSVQK LVTDEDVFPT KYGREFPSSF ESLVRKICRH LFHVLAHIYW AHFKETLALE LHGHLNTLYV HFILFAREFN LLDPKETAIM DDLTEVLCSG AGGVHSGGSG DGAGSGGPGA QNHVKER
Explore MOB kinase activator 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets