About MOB kinase activator 3C
MOB kinase activator 3C (MOB3C) is a protein
from Homo sapiens identified by UniProt accession
Q70IA8, 216 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | MOB kinase activator 3C |
|---|
| UniProt accession | Q70IA8 |
|---|
| Gene | MOB3C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 216 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.55
- platelet component distribution width · score 0.22
- nicotine dependence · score 0.02
- smoking status measurement · score 0.02
- systemic juvenile idiopathic arthritis · score 0.01
- inherited lipid metabolism disorder · score 0.01
- chronic kidney disease · score 0.01
- Salmonella Infections · score 0.00
- MALT lymphoma · score 0.00
- Hypertriglyceridemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q70IA8-F1 | alphafold | PREDICTED | 88.86 | — |
Amino-acid sequence (216 residues)
MALCLKQVFA KDKTFRPRKR FEPGTQRFEL YKKAQASLKS GLDLRSVVRL PPGENIDDWI AVHVVDFFNR INLIYGTMAE RCSETSCPVM AGGPRYEYRW QDERQYRRPA KLSAPRYMAL LMDWIEGLIN DEEVFPTRVG VPFPKNFQQV CTKILTRLFR VFVHVYIHHF DSILSMGAEA HVNTCYKHFY YFIREFSLVD QRELEPLREM TERICH
Explore MOB kinase activator 3C with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets