About Protein FRA10AC1
Protein FRA10AC1 (FRA10AC1) is a protein
from Homo sapiens identified by UniProt accession
Q70Z53, 315 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Protein FRA10AC1 |
|---|
| UniProt accession | Q70Z53 |
|---|
| Gene | FRA10AC1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 315 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodevelopmental disorder with growth retardation, dysmorphic facies, and corpus callosum abnormalities · score 0.60
- Neurodevelopmental disorder · score 0.37
- genetic disorder · score 0.18
- DNA methylation · score 0.13
- soluble triggering receptor expressed on myeloid cells 2 measurement · score 0.02
- myelodysplastic syndrome · score 0.00
- type 1 diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q70Z53-F1 | alphafold | PREDICTED | 72.19 | — |
Amino-acid sequence (315 residues)
MHGHGGYDSD FSDDERCGES SKRKKRTVED DLLLQKPFQK EKHGKVAHKQ VAAELLDREE ARNRRFHLIA MDAYQRHTKF VNDYILYYGG KKEDFKRLGE NDKTDLDVIR ENHRFLWNEE DEMDMTWEKR LAKKYYDKLF KEYCIADLSK YKENKFGFRW RVEKEVISGK GQFFCGNKYC DKKEGLKSWE VNFGYIEHGE KRNALVKLRL CQECSIKLNF HHRRKEIKSK KRKDKTKKDC EESSHKKSRL SSAEEASKKK DKGHSSSKKS EDSLLRNSDE EESASESELW KGPLPETDEK SQEEEFDEYF QDLFL
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