Ubiquitin-conjugating enzyme E2 R2 (UBE2R2)

About Ubiquitin-conjugating enzyme E2 R2

Ubiquitin-conjugating enzyme E2 R2 (UBE2R2) is a protein from Homo sapiens identified by UniProt accession Q712K3, 238 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Ubiquitin-conjugating enzyme E2 R2
UniProt accession	Q712K3
Gene	UBE2R2
Organism	Homo sapiens
Length	238 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q712K3-F1	alphafold	PREDICTED	85.25	—

Amino-acid sequence (238 residues)

MAQQQMTSSQ KALMLELKSL QEEPVEGFRI TLVDESDLYN WEVAIFGPPN TLYEGGYFKA HIKFPIDYPY SPPTFRFLTK MWHPNIYENG DVCISILHPP VDDPQSGELP SERWNPTQNV RTILLSVISL LNEPNTFSPA NVDASVMFRK WRDSKGKDKE YAEIIRKQVS ATKAEAEKDG VKVPTTLAEY CIKTKVPSND NSSDLLYDDL YDDDIDDEDE EEEDADCYDD DDSGNEES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards