About Cystin-1
Cystin-1 (CYS1) is a protein
from Homo sapiens identified by UniProt accession
Q717R9, 158 residues long.
MolForge cross-references it against 0 known binders and
208 disease associations.
Target properties
| Protein name | Cystin-1 |
|---|
| UniProt accession | Q717R9 |
|---|
| Gene | CYS1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 158 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (208)
Diseases linked to this target (Open Targets).
- autosomal recessive polycystic kidney disease · score 0.35
- neurodegenerative disease · score 0.35
- body height · score 0.34
- chronic bronchitis · score 0.28
- chronic obstructive pulmonary disease · score 0.28
- erythrocyte count · score 0.19
- sitting height measurement · score 0.18
- forced expiratory volume · score 0.18
- lean body mass · score 0.12
- vital capacity · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q717R9-F1 | alphafold | PREDICTED | 64.90 | — |
Amino-acid sequence (158 residues)
MGSGSSRSSR TLRRRRSPES LPAGPGAAAL EGGTRRRVPV AAAEVPGAAA EEAPGRDPSP VAPPDGRDET LRLLDELLAE SAAWGPPEPA PRRPARLRPT AVAGSAVCAE QSTEGHPGSG NVSEAPGSGR KKPERPAAIS YDHSEEGLMA SIEREYCR
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