Histone H3.2 (H3C15)

About Histone H3.2

Histone H3.2 (H3C15) is a protein from Homo sapiens identified by UniProt accession Q71DI3, 136 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Histone H3.2
UniProt accession	Q71DI3
Gene	H3C15
Organism	Homo sapiens
Length	136 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

viral disease · score 0.50
infectious disease · score 0.50
cancer · score 0.37
melanoma · score 0.37
breast carcinoma · score 0.37
age at menopause · score 0.07
serum urea measurement · score 0.04
triglyceride measurement · score 0.04
high density lipoprotein cholesterol measurement · score 0.03
vital capacity · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q71DI3-F1	alphafold	PREDICTED	85.98	—

Amino-acid sequence (136 residues)

MARTKQTARK STGGKAPRKQ LATKAARKSA PATGGVKKPH RYRPGTVALR EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSSAV MALQEASEAY LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards